SSPE

classic Classic list List threaded Threaded
3 messages Options
Reply | Threaded
Open this post in threaded view
|

SSPE

Amber
I know its related to m, m, r, and I apologize for not knowing this, but what exactly is SSPE?

Why does it take so long to present itself?

Reply | Threaded
Open this post in threaded view
|

Re: SSPE

Science Mom
Administrator
Here is some basic information about SSPE:  http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002392/
It takes so long to present because it is an insidious course.  Think of a brain tumour, which people can live with for years and never even know they have until the growth becomes so large it begins to affect neurobehaviour.  It is only associated with wild-type measles disease and not the vaccine.

SM
Reply | Threaded
Open this post in threaded view
|

Re: SSPE

Catherina
Administrator
In reply to this post by Amber
Hi Amber,

SSPE is a late consequence of measles virus infection of the brain. Essentially, a small mutation in the measles virus gives it the capacity to hide in the brain for several years (usually 5 to 7, but it can be much shorter or longer) and then it starts to affect the brain quite quickly - the kids get seizures, can go blind, lose all abilities and eventually die (usually within a year or two, but Micha has been blind and in a wake coma for the past 6 or 7 years).

http://www.ninds.nih.gov/disorders/subacute_panencephalitis/subacute_panencephalitis.htm